{"product_id":"berberine","title":"Berberine","description":"\u003cp\u003eWHAT IT DOES\u003c\/p\u003e\u003cp\u003eMETABOLIC SUPPORT*\u003c\/p\u003e\u003cp\u003eBerberine offers metabolic support for glucose and lipid metabolism.* It also supports healthy blood sugar and insulin levels already within a normal range.* Also supports healthy gastrointestinal function.* \u003c\/p\u003e\u003cp\u003eHOW IT WORKS\u003c\/p\u003e\u003cp\u003eClinical studies demonstrate that berberine supports healthy lipid metabolism and cholesterol homeostasis.*\u003csup\u003e1-6\u003c\/sup\u003e Berberine can activate an important metabolic enzyme known as adenosine monophosphate-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis.* Mechanistic research in vitro and in vivo suggests that berberine can decrease cholesterol and triglyceride synthesis by activating AMPK.\u003csup\u003e7-9\u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003eIn addition to supporting lipid metabolism, berberine supports healthy glucose metabolism and blood sugar management already within a normal range.*\u003csup\u003e2-5\u003c\/sup\u003e Mechanistic research in vitro suggests that berberine can support healthy glucose regulation through promoting glucose uptake in cells via GLUT4 translocation.\u003csup\u003e7\u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003eREFERENCES\u003c\/p\u003e\u003csmall\u003e\u003col\u003e\n\u003cli\u003e Kong W et al. Nat Med. 2004;10(12):1344-51.\u003c\/li\u003e\n\u003cli\u003e Yin J et al. Metabolism. 2008;57(5):712-7.\u003c\/li\u003e\n\u003cli\u003e Zhang Y et al. J Clin Endocrinol Metab. 2008;93(7):2559-2565.\u003c\/li\u003e\n\u003cli\u003e Yang J et al. Evid Based Complement Alternat Med. 2012;2012:363845.\u003c\/li\u003e\n\u003cli\u003e Perez-Rubio K et al. Metab Syndr Relat Disord. 2013;11(5):366-9.\u003c\/li\u003e\n\u003cli\u003e  Cao C et al. Exp Ther Med. 2019;17(4):3009-3014.\u003c\/li\u003e\n\u003cli\u003e Lee YS et al. Diabetes. 2006;55:2256-64.\u003c\/li\u003e\n\u003cli\u003eBrusq JM et al. J Lipid Res. 2006;47(6):1281-8.\u003c\/li\u003e\n\u003cli\u003e Jiang D et al. Lipids Health Dis. 2016;15:214.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/small\u003e","brand":"ITI","offers":[{"title":"60 capsules","offer_id":44397803897046,"sku":"10711","price":32.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/9110\/4982\/files\/202603111926_583240e8-97da-42dc-a8e4-f2df23cda5ce.png?v=1776810274","url":"https:\/\/naturesway.mom\/products\/berberine","provider":"Nature's Way®","version":"1.0","type":"link"}